Two coherent sources of sound/light/water waves produce waves that impact on a screen.
The path difference is the difference in distance covered by the waves travelling from the source to the screen.
If Wave A from speaker A travels 10 m to get to a point on a screen and Wave B from speaker B travels 20 m to get to the SAME POINT, the path difference is 10 m. P.D. is usually expressed in terms of wavelengths. If the wavelengths of A and B were 5m then the P.D. can be said to be 2 lambda.
When the P.D = 0 phase difference = 0 hence constructive interference occurs i.e. the two waves superimpose such that the vector sum of their amplitudes leads to a doubling of amplitude.
When P.D. = whole no. of wavelengths constructive interference occurs.
When P.D. = non-integer, half wavelengths you have destructive interference.