Can u please help me in these questions
1) Explain what is meant by the term genetic carrier?
A genetic carrier (or just carrier), is a person or other organism that has inherited a genetic trait or mutation, but who does not display that trait or show symptoms of the disease. They are, however, able to pass the gene onto their offspring, who may then express the gene. This phenomenon is a direct result of the recessive nature of many genes.
For example, the daughters of Queen Victoria, the princesses Alice and Beatrix, were carriers of the X-linked hemophilia gene (more precisely, an abnormal allele of a gene necessary to produce one of the blood clotting factors). Both had children who continued to pass the gene to succeeding generations of the royal houses of Spain and Russia, into which they married. Males who carried the altered gene had hemophilia, while females simply passed it to about half of their children.
-Wikipedia.
2) One of the polypeptide chains in the haemoglobin of a person with sickle cell anaemia has a change in one of its amino acids.Explain how change in
DNA can lead to a change in a single amino acid in polypeptide chain.
I appreciate ur help!!
Each base pairing in the DNA sequence codes for a different amino-acid. So, a change in these base-pairing will change the aminoacid it is supposed to code for. This will alter the polypeptide chain.