Qualification > Sciences
Edexcel A2 Biology Unit 4 Revision for 15 June 2012 Examination!
MKh:
I have a doubt. Please help me if anyone can.
In topic 6 of unit 4 bio, what do we have to know for the following specification point:
13. Explain the roles of antigens and antibodies in the body’s immune response including the involvement of plasma cells, macrophages and antigen-presenting cells.
And does anyone have any specfc questions on the Core Practicals in unit 4?
Thanks.
Romeesa-Chan:
--- Quote from: MKh on April 22, 2012, 02:01:53 pm ---13. Explain the roles of antigens and antibodies in the body’s immune response including the involvement of plasma cells, macrophages and antigen-presenting cells.
--- End quote ---
Any substance that raises an alarm in the body, causing the immune system to react to and attack it is called an antigen. The main function of antigen-presenting cells (APCs) is to help lymphocytes recognize antigens on foreign cells (including cancer cells). Antigen-presenting cells include monocytes, macrophages, and dendritic cells.
Plasma cells release antibodies that bind (attach) only to that antigen. The antibodies then help kill any cells that have the antigen. The antibodies may destroy them directly or they may serve as a marker for other immune system cells, such as T cells, to destroy them.
Macrophages, capable of surrounding and "eating" unwanted cells. They then present antigens from the devoured cells on their outer surface, so that lymphocytes can recognize the foreign antigens if they are found in the body later on.
[source: http://www.cancer.org/Treatment/TreatmentsandSideEffects/TreatmentTypes/Immunotherapy/immunotherapy-immune-system]
MKh:
--- Quote from: Romeesa-Chan on April 22, 2012, 03:40:25 pm ---Any substance that raises an alarm in the body, causing the immune system to react to and attack it is called an antigen. The main function of antigen-presenting cells (APCs) is to help lymphocytes recognize antigens on foreign cells (including cancer cells). Antigen-presenting cells include monocytes, macrophages, and dendritic cells.
Plasma cells release antibodies that bind (attach) only to that antigen. The antibodies then help kill any cells that have the antigen. The antibodies may destroy them directly or they may serve as a marker for other immune system cells, such as T cells, to destroy them.
Macrophages, capable of surrounding and "eating" unwanted cells. They then present antigens from the devoured cells on their outer surface, so that lymphocytes can recognize the foreign antigens if they are found in the body later on.
Thanks.
[source: http://www.cancer.org/Treatment/TreatmentsandSideEffects/TreatmentTypes/Immunotherapy/immunotherapy-immune-system]
--- End quote ---
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